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LifePlus provides state-of-the-art scientific biomedical methods
and high experience in telomere length measurement and telomerase activity estimation.
Telomere Length Measurement by metaphase Q-FISH technology
LifePLus offers the most accurate and precise technology since is the only that can measure only the telomere ends of each chromosome avoiding the false measurement of the interstitial telomere regions the chromosomes.
Our technology is the only that:
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Allow the recognition of telomere-free ends which are leading to chromosomal instability and are linked with age-related diseases
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Measure each telomere end in each chromosome in each cell
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Provide information about variation in the length of telomeres between different chromosomes
The analysis provides:
Average Telomere Length
Median Telomere Length
Median of short telomeres
Percentage of critically short telomeres
Percentage of critically long telomeres
Biological age
The rate of telomere shortening
Telomere Length Measurement by Q-PCR technology
The analysis is suitable for isolated DNA samples
Provides an average of telomere length
Is suitable for research population studies since it indicates the trend of telomere length in a sample
Telomerase Activity Estimation
In order for the cells to sustain the integrity of DNA during each replication, a specialised enzyme called telomerase sustains the edges of DNA strands in each chromosome delaying the overall process of DNA loss.
Telomerase has been a target for therapeutic interventions for several decades, as its regulation is associated with numerous diseases.
Environmental and lifestyle factors seem to contribute to telomerases activity.
Reduced telomerase activity may explain why telomeres shorten faster in pathological conditions. More precisely, telomerase overexpression is related to cancer development, whereas telomerase inhibition is combined with age-related diseases.
Hence telomerase activity can be a useful real life risk simulation biomarker.
Learn the expression levels of telomerase enzyme
Learn if a substance activates or inhibits telomerase expression in cell or tissue samples
using LifePlus’s technology and get a full report with statistical analysis.